5-alpha-dihydrotestosterone elevations associated with phentermine use
نویسندگان
چکیده
منابع مشابه
Pulmonary Hypertension Associated with Use of Phentermine
Weight-control drugs (known as anorexigens) such as fenfluramine have been linked with pulmonary hypertension in previous reports. In our case, a 29 year old woman was admitted for shortness of breath and was diagnosed with pulmonary hypertension. Three months ago, she had been taking phentermine for five weeks. Other factors that might have contributed to the development of pulmonary hypertens...
متن کاملRE: Pulmonary Hypertension Associated with Use of Phentermine?
• The authors have no financial conflicts of interest. which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. 1 reported a case of a 29 year-old obese woman who was hospitalized with pulmonary arterial hypertension (PAH) and a history of having tak-en phentermine hydrochloride 37.5 milligrams daily for 35 days. ...
متن کامل[Dihydrotestosterone formation (5 alpha-reductase activity) in cultured human skin fibroblasts].
Testosterone secreted from the testis is converted to dihydrotestosterone (DHT) in target tissues by 5 alpha-reductase and DHT exerts its action on the nucleus. Since skin is one of the target tissues of androgen we established a system for culturing human skin fibroblasts, and we investigated the conversion of testosterone to DHT in genital and nongenital skin fibroblasts obtained from males a...
متن کاملPossible association of ischemic stroke with phentermine.
BACKGROUND AND PURPOSE Some commonly used anorexiants, including methamphetamine and phenylpropanolamine, have been associated with stroke. Because phentermine is an anorexiant with a chemical structure similar to that of amphetamines, similar side effects might be expected. CASE DESCRIPTIONS Two patients using phentermine (one was also using phendimetrazine) developed ischemic cerebrovascula...
متن کاملRisk of gynecomastia and breast cancer associated with the use of 5-alpha reductase inhibitors for benign prostatic hyperplasia
BACKGROUND Clinical trial results suggest that 5-alpha reductase inhibitors (5ARIs) for the treatment of benign prostatic hyperplasia (BPH) may increase the risk of gynecomastia and male breast cancer, but epidemiological studies have been limited. PATIENTS AND METHODS We conducted a cohort study with nested case-control analyses using the UK Clinical Practice Research Datalink. We identified...
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ژورنال
عنوان ژورنال: Therapeutic Advances in Endocrinology and Metabolism
سال: 2018
ISSN: 2042-0188,2042-0196
DOI: 10.1177/2042018818776158